Recent Tuberculosis News
[Editorial] Global health in 2012: development to sustainability
Posted from MedWorm: Tuberculosis 4 days ago
Tuberculosis : Tuberculosis
In 2012 there will be a major strategic shift in global health, away from development and towards sustainability. Since 2000, the Millennium Development Goals (MDGs), driven by a macroeconomic diagnosis of global poverty, have focused on investment in a small number of diseases as the most effective... (original story)
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Structures of new crystal forms of Mycobacterium tuberculosis peptidyl-tRNA hydrolase and functionally important plasticity of the molecule
Posted from MedWorm: Tuberculosis 4 days ago
Tuberculosis : Tuberculosis
The X-ray structures of new crystal forms of peptidyl-tRNA hydrolase from M. tuberculosis reported here and the results of previous X-ray studies of the enzyme from different sources provide a picture of the functionally relevant plasticity of the protein molecule. The new X-ray results confirm the... (original story)
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In this issue
Posted from MedWorm: Tuberculosis 4 days ago
Tuberculosis : Tuberculosis
AbstractCover imageThe cover is based on a spinal cord histology section taken from a TNFR2−/− mouse adoptively transferred with TNFR2−/− Treg cells prior to immunization with MOG35–55 to induce EAE. The section is stained with Luxol Fast blue to detect demyelination; Luxol Fast Red, which... (original story)
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Mycobacterium tuberculosis Sonicate–Induced IFNγ, CXCL10 and IL10 can Differentiate Severity in Tuberculosis
Posted from MedWorm: Tuberculosis 14 days ago
Tuberculosis : Tuberculosis
AbstractImproved tools are required to study immunopathogenesis of tuberculosis (TB). Mycobacterium tuberculosis antigen‐stimulated T cell‐based assays can detect TB but are less effective when responses are compromised such as in severe disease. We investigated immune responses to M. tuberculo... (original story)
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New Tuberculosis Strain Thwarts All Antibiotics
Posted from MedWorm: Tuberculosis 14 days ago
Tuberculosis : Tuberculosis
Physicians in India have discovered a strain of tuberculosis they call 'TDR' for 'Totally Drug-Resistant'--meaning there is no antibiotic available to fight it. Maryn McKenna, author of Superbug, discusses the possible origins of the strain, and what options--if any--doctors have to treat it.»... (original story)
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Aeras and CNBG sign agreement on tuberculosis vaccine R&D
Posted from MedWorm: Tuberculosis 14 days ago
Tuberculosis : Tuberculosis
(Aeras) Aeras and the China National Biotec Group announce that they have reached final agreement to jointly develop new tuberculosis vaccines. The agreement between the leading non-profit developer of TB vaccine candidates and the largest biotechnology corporation in China signals a commitment by b... (original story)
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Comparison of interferon‐γ‐, interleukin (IL)‐17‐ and IL‐22‐expressing CD4 T cells, IL‐22‐expressing granulocytes and proinflammatory cytokines during latent and active tuberculosis infection
Posted from MedWorm: Tuberculosis 14 days ago
Tuberculosis : Tuberculosis
In this study, we investigated the role and expression of T helper type 17 (Th17) cells and Th17 cytokines in human tuberculosis. We show that the basal proportion of interferon (IFN)‐γ‐, interleukin (IL)‐17‐ and IL‐22‐expressing CD4+ T cells and IL‐22‐expressing granulocytes in per... (original story)
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Long‐term persistence of BCG Pasteur in lungs of C57BL/6 mice following intranasal infection
Posted from MedWorm: Tuberculosis 14 days ago
Tuberculosis : Tuberculosis
AbstractDifferent Mycobacterium bovis BCG (BCG) vaccine substrains may vary in their efficacy. Here we describe differences in disease progression and pathology in the lungs of female C57BL/6‐mice infected intranasally with,BCG Russia or BCG Pasteur and followed for 17 months. The lungs were inves... (original story)
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Three-year study identifies key interventions to reduce maternal, newborn and child deaths
Posted from WHO news 20 days ago
Tuberculosis : Tuberculosis news
15 December 2011 -- About 358 000 women still die each year during pregnancy and childbirth; 7.6 million children die before the age of 5 annually. A new global consensus has agreed on the key evidence-based interventions that will sharply reduce these numbers. The study, Essential interventions, co... (original story)
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WHO concerned that new H5N1 influenza research could undermine the 2011 Pandemic Influenza Preparedness Framework
Posted from WHO news 20 days ago
Tuberculosis : Tuberculosis news
30 December 2011 -- WHO takes note that studies undertaken by several institutions on whether changes in the H5N1 influenza virus can make it more transmissible between humans have raised concern about the possible risks and misuses associated with this research. WHO is also deeply concerned about t... (original story)
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